Growing the phenotype of chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) in children

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clippers: chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids

a novel type of brainstem-predominant encephalomyelitis was first described as chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (clippers) in 2010 by pittocket al and then few additional patients were reported. here we report a 50-year-old iranian male who presented with a number of clinical features described as typical for clippers. the association...

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Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids (CLIPPERS) with Limbic Encephalitis

Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is an inflammatory central nervous system disorder that mainly involves in the brainstem, basal ganglia and cerebellum. We herein report the case of a patient with CLIPPERS, which was diagnosed based on the clinical and radiological features. After initially responded to steroid treatment, t...

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[CLIPPERS (chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids)].

Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) has been recently identified as an inflammatory central nervous system (CNS) disorder. Punctate and curvilinear gadolinium enhancement (peppering) the pons is a characteristic magnetic resonance imaging (MRI) feature of CLIPPERS. Pathogenesis of this disorder remains unknown. A specific seru...

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Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS)

1 Department of Neurology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA 2 Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA 3 Department of Neurology, Ghent University Hospital, Ghent, B.9000, Belgium 4 Department of Radiology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA 5 Department of Neurology, Mayo Clinic Co...

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Chronic hepatitis B infection presenting with chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS): a case report

INTRODUCTION Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids is a brainstem disorder characterized by perivascular pathologic reaction with lymphocyte infiltration and leading to diplopia, facial palsy, dysarthria, and gait ataxia. It was thought to be an autoimmune disorder without distinct pathogenesis. Chronic hepatitis B virus infection has been...

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ژورنال

عنوان ژورنال: Developmental Medicine & Child Neurology

سال: 2018

ISSN: 0012-1622,1469-8749

DOI: 10.1111/dmcn.14043